After moving to The Coterie in Downtown Los Angeles, Callie and Mariana Foster realize that living on their own is not all that it's cracked up to be.

Picking up one year after the events of the final broadcast episode of "The Good Wife", an enormous financial scam has destroyed the reputation of a young lawyer, Maia Rindell, while simultaneously wiping out her mentor and godmother Diane Lockhart's savings. Forced out of her law firm, now called "Lockhart, Deckler, Gussman, Lee, Lyman, Gilbert, Lurie, Kagan, Tannebaum & Associates", they join Lucca Quinn at one of Chicago's preeminent law firms.

Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join a prestigious hospital's surgical unit. Unable to personally connect with those around him, Shaun uses his extraordinary medical gifts to save lives and challenge the skepticism of his colleagues.